Past investigations of Omicron's spike changes - especially in the locale that perceives receptors on human cells - propose that the variation will dull the power of killing antibodies. For example, in a September 2021 Nature paper2, a group co-drove by Paul Bieniasz, a virologist at Rockefeller University in New York City, designed an exceptionally transformed form of spike - in an infection unequipped for causing COVID-19 - that imparts various transformations to Omicron. https://www.goodmottoblog.com/2022/02/blog-post.html