Understanding (Q-TOF) Mass Spectrometer: Applications in Drug Discovery and Development

0
166

Mass spectrometry is an analytical technique used to identify the mass of molecules by measuring the mass-to-charge ratio and abundance of gas phase ions. During analysis, molecules are converted to ions which are then detected by the instrument based on their mass-to-charge ratios. Mass spectrometers have been used in various applications such as proteomics, metabolomics, environmental analysis and more.

Quadrupole-Time of Flight Technology

One popular type of mass spectrometer is the quadrupole-time of flight or Q-TOF system. In a Q-TOF Mass Spectrometer, ions are separated based on their mass-to-charge ratios in both the quadrupole mass filter and orthogonal time-of-flight analyzer. The quadrupole is used to selectively transmit ions within a narrow mass window into the time-of-flight tube for high resolution mass measurement.

Quadrupole Mass Filte
r

The quadrupole mass filter utilizes four parallel metal rods that an RF voltage as well as a DC voltage are applied to. Ions entering the quadrupole travel down its central axis and are filtered based on their stability in the oscillating field produced between the rods. Only ions with a specific mass-to-charge ratio will successfully traverse the quadrupole whereas all other ions will collide with the rods and be neutralized. This allows the quadrupole to function as a high-pass, low-pass or band-pass filter for ion transmission.

 

Get More Insights on- Q-TOF Mass Spectrometer

Cerca
Sponsorizzato
Categorie
Leggi tutto
Altre informazioni
Medium Voltage Cables and Accessories Market Size, Share - Industry Report 2032
Medium Voltage Cables and Accessories Market Analysis 2024-2032 The Global Medium Voltage Cables...
By Sager Chavan 2024-01-05 11:46:48 0 2K
Altre informazioni
Sodium Sulfide Market Cost Structure and Growth Opportunities 2030
Market Overview:Sodium sulfide is crystalline solid of brick red or yellow color. Sodium Sulfide...
By Yogesh Joshi 2021-11-29 10:33:56 0 2K
Art
SHOT 1500 NIGHT 6000 CALL GIRLS IN INA Market 9999894380
Call Me Candy 9999894380 I, provide In Delhi NCR Female Escorts Sex Service Female Escorts In...
By Preeya Kapoor 2020-10-10 07:03:44 0 2K
Altre informazioni
Красивые стопы: как вернуть им здоровый вид после зимнего сезона
Зимний сезон не только заставляет нас носить теплую обувь, но и оставляет неприятные последствия...
By Alexei Fokin 2023-02-25 11:35:07 0 1K
Altre informazioni
Insulating Glass Window market specifications, detailed research analysis report 2022– 2030
No. of Pages- 110+ List of tables- 20+ List of Figures- 20+ According to the research report...
By Edwin Hall 2022-07-21 06:34:14 0 2K