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NEW QUESTION 48
Which of the following BEST describes the content of the "Physical, Chemical, and
Pharmaceutical Properties and Formulation" section of an IB?

  • A. A brief summary of relevant physical, chemical, and pharmaceutical properties:
    instructions for storage and handling of the dosage form: and a description of the formulation
  • B. A detailed summary of the physical and chemical properties of the drug product with a signed expert statement addressing the suitability and stability of the formulation for its intended use
  • C. A review of available data to support the determination of the chemical structure and physical attributes of the drug substance plus batch analysis and stability data for the finished formulation
  • D. A description and flow chart illustrating the synthetic route for the active ingredient and the preparation method of the finished product

Answer: A

 

NEW QUESTION 49
Company X encounters challenges in the global life cycle management of its medical devices. Which of the following Is MOST appropriate for improving product life cycle management?

  • A. Identify countries where special requirements exist during the product development phase.
  • B. Utilize the STED template to complete global requirements.
  • C. Initiate a global submission process after all submission data are finalized.
  • D. Plan regulatory approval update meetings with senior management and stakeholders.

Answer: A

 

NEW QUESTION 50
After submission to the regulatory authority, a substantial error was found in the application. In order to resolve this issue, what should be done FIRST?

  • A. Verify the procedure in the regulation for the corrections.
  • B. Resubmit the entire package.
  • C. Inform upper management immediately.
  • D. Contact the legal department and ask them how to proceed.

Answer: A

 

NEW QUESTION 51
During several monitoring visits, a clinical trial monitor identifies serious and repeated noncompliance on the part of the PI. What action should the sponsor take?

  • A. Inform the institution that granted a medical license to the Pi.
  • B. Terminate the PI and inform the regulatory authorities.
  • C. Increase the frequency of monitoring visits.
  • D. Send a letter of complaint to the Ethics Committee that approved the site.

Answer: B

 

NEW QUESTION 52
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