What is Glutathione and how it works?

Glutathione is the body's major antioxidant and is the most strong and potent antioxidant that detoxifies the entire body.

This super-principal antioxidant's function is to assist our bodies in protecting themselves against free radicals, waste, and potentially all hazardous chemicals while also allowing them to replenish and preserve all other antioxidants in the body.

One of the most significant antioxidants in the human body is glutathione. It is necessary for liver health and is used to detoxify the body.

The body's ability to manufacture glutathione decreases with age. Furthermore, a variety of chemicals, including alcohol, narcotics, and other compounds, can lower glutathione levels in the body.

Conjugation with glutathione is one of the key detoxification routes in phase II (tripeptide consisting of three amino acids - cysteine, glutamic acid, and glycine).

Glutathione conjugation, in essence, aids in the detoxification and elimination of poisons and toxins in the liver, lungs, intestines, and kidneys. Conjugation of glutathione with toxins aids in the detoxification and elimination of fat-soluble poisons and heavy metals. Other environmental pollutants such as solvents, herbicides, fungicides, polycyclic aromatic hydrocarbons, and lipid peroxides are all detoxed by it.

Reduced glutathione conjugation capacity may lead to an increase in toxic load and oxidative stress.

S acetyl glutathione protects the body against oxidative stress (especially by reducing hydrogen peroxide and by regenerating oxidised vitamins C and E). Glutathione levels must be enough for these fat-soluble molecules to be eliminated. As a result, the liver is protected from the detrimental effects of poisonous substances and their neutralisation is aided.

Glutathione is depleted quicker than the body can generate or absorb it from food when exposed to high quantities of pollutants. Glutathione insufficiency causes a variety of diseases. A glutathione deficiency can be caused by disorders that increase the requirement for glutathione, or by dietary deficiencies that prevent it from being synthesised, but it can also be caused by diseases that prevent it from being formed.

Furthermore, smoking raises the rate at which glutathione is used, both for nicotine detoxification and for the neutralisation of free radicals created by tobacco smoke.