QuickBooks crashes on its own for no apparent reason. QuickBooks error 15227 can be caused by a number of factors, including corrupted or damaged QuickBooks software, incomplete installation, virus or malware intrusion, or accidentally deleting some necessary QuickBooks files. Some solutions can be used to resolve Quickbooks error 15227. To begin, repair the registry entries and run a virus or malware scan to resolve the issue. You can also use disc cleanup to get rid of temporary files and junk files. Ensure that the PC device drivers are up to date and that any recent changes are undone. If the problem persists, you must uninstall and reinstall QuickBooks.